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LIFE HAPPENS. Be Prepared.®

Anaphylaxis is unpredictable. When it comes to potentially life-threatening allergic reactions (anaphylaxis), you need to have a plan. Your plan should include avoiding known allergens, recognizing the signs and symptoms of anaphylaxis, having access to two epinephrine auto-injectors at all times and seeking immediate emergency medical care should anaphylaxis occur.

Maybe you’ve heard of EPIPEN Auto-Injector or the Authorized Generic for EPIPEN …but what are they?

EPIPEN 0.3 mg and EPIPEN JR®  (epinephrine injection, USP) 0.15 mg Auto-Injectors are for people who have a history of life-threatening allergic reactions (anaphylaxis) to things like bee stings, peanuts or seafood, or are at increased risk for these reactions. EPIPEN 0.3 mg and EPIPEN JR are self-injectable devices (auto-injectors) that contain epinephrine. According to National Food Allergy Guidelines, epinephrine is the first-line treatment for life-threatening allergic reactions. And now you have a choice—EPIPEN Auto-Injector or its authorized generic

Be prepared to act fast.

If you, your child or someone you're caring for shows signs or symptoms of anaphylaxis, administer EPIPEN or EPIPEN JR Auto-Injector, or their authorized generics, immediately as prescribed and seek emergency medical care.

Have access to two doses of epinephrine at all times.

EPIPEN 2-PAK® and EPIPEN JR 2-PAK® cartons, as well as their authorized generics, contain two epinephrine auto-injectors (plus one Trainer that does not contain epinephrine or a needle). This follows national food allergy guidelines that recommend people at increased risk for anaphylaxis have two doses of epinephrine available at all times.

EPIPEN 2-PAK, EPIPEN JR 2-PAK and their authorized generics provide a second dose of epinephrine, which might be needed during a life-threatening allergic reaction. One reason is in case of what is called a protracted reaction—where symptoms may persist even after a first dose of epinephrine is administered. Another situation that may require a second dose of epinephrine is called a biphasic reaction—where symptoms may appear to go away but then come back, typically within 8 hours (sometimes up to 72 hours) after the initial allergic reaction.

More than two doses of epinephrine for a single episode should be administered only under direct medical supervision.Talk to your healthcare professional if you need additional cartons of EPIPEN 2-PAK, EPIPEN JR 2-PAK or their authorized generics to keep at work, school or other locations to help you have immediate access to two epinephrine auto-injectors in case of a life-threatening allergic reaction.

Every carton of EPIPEN 2-PAK, EPIPEN JR 2-PAK and their authorized generics includes a Trainer auto-injector.

Knowing how to correctly use your EPIPEN or EPIPEN JR Auto-Injector, or their authorized generics, is essential, which is why every carton includes a needle-free, epinephrine-free Trainer. Practice with your Trainer and watch our step-by-step video. Also, make sure that anyone who may need to administer EPIPEN or EPIPEN JR Auto-Injector, or their authorized generics, does the same.

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IMPORTANT SAFETY INFORMATION (the following information applies to both EPIPEN and its Authorized Generic)

Use EPIPEN (epinephrine injection, USP) 0.3 mg or EPIPEN JR (epinephrine injection, USP) 0.15 mg Auto-Injectors right away when you have an allergic emergency (anaphylaxis). Get emergency medical help right away. You may need further medical attention. Only a healthcare professional should give additional doses of epinephrine if you need more than two injections for a single anaphylactic episode. EPIPEN or EPIPEN JR should only be injected into the middle of your outer thigh (upper leg), through clothing if necessary. Do not inject into your veins, buttocks, fingers, toes, hands or feet. Hold the leg of young children firmly in place before and during injection to prevent injuries. In case of accidental injection, please seek immediate medical treatment.

Rarely, patients who have used EPIPEN or EPIPEN JR may develop an infection at the injection site within a few days. Some of these infections can be serious. Call your healthcare professional right away if you have any of the following at an injection site: redness that does not go away, swelling, tenderness, or the area feels warm to the touch.

Tell your healthcare professional about all of your medical conditions, especially if you have asthma, a history of depression, thyroid problems, Parkinson’s disease, diabetes, high blood pressure or heart problems, have any other medical conditions, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Be sure to also tell your healthcare professional all the medicines you take, especially medicines for asthma. If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have longer lasting side effects when you use EPIPEN or EPIPEN JR.

Common side effects include fast, irregular or “pounding” heartbeat, sweating, nausea or vomiting, breathing problems, paleness, dizziness, weakness, shakiness, headache, feelings of over excitement, nervousness or anxiety. These side effects usually go away quickly if you lie down and rest. Tell your healthcare professional if you have any side effect that bothers you or that does not go away.

Indications (the following information applies to both EPIPEN and its Authorized Generic)

EPIPEN and EPIPEN JR  Auto-Injectors are for the emergency treatment of life-threatening allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for people who are at increased risk for these reactions. EPIPEN and EPIPEN JR are intended for immediate administration as emergency supportive therapy only. Seek immediate emergency medical help right away.


 Please see the full Prescribing Information and Patient Information for EPIPEN.

Please see the full Prescribing Information and Patient Information for the Authorized Generic for EPIPEN.

For additional information please contact us at 800-796-9526.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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IMPORTANT SAFETY INFORMATION (the following information applies to both EPIPEN and its Authorized Generic)

Use EPIPEN (epinephrine injection, USP) 0.3 mg or EPIPEN JR (epinephrine injection, USP) 0.15 mg Auto-Injectors right away when you have an allergic emergency (anaphylaxis). Get emergency medical help right away. You may need further medical attention. Only a healthcare professional should give additional doses of epinephrine if you need more than two injections for a single anaphylactic episode. EPIPEN or EPIPEN JR should only be injected into the middle of your outer thigh (upper leg), through clothing if necessary. Do not inject into your veins, buttocks, fingers, toes, hands or feet. Hold the leg of young children firmly in place before and during injection to prevent injuries. In case of accidental injection, please seek immediate medical treatment.

IMPORTANT SAFETY INFORMATION (the following information applies to both EPIPEN and its Authorized Generic)

Use EPIPEN (epinephrine injection, USP) 0.3 mg or EPIPEN JR (epinephrine injection, USP) 0.15 mg Auto-Injectors right away when you have an allergic emergency (anaphylaxis). Get emergency medical help right away. You may need further medical attention. Only a healthcare professional should give additional doses of epinephrine if you need more than two injections for a single anaphylactic episode. EPIPEN or EPIPEN JR should only be injected into the middle of your outer thigh (upper leg), through clothing if necessary. Do not inject into your veins, buttocks, fingers, toes, hands or feet. Hold the leg of young children firmly in place before and during injection to prevent injuries. In case of accidental injection, please seek immediate medical treatment.

Rarely, patients who have used EPIPEN or EPIPEN JR may develop an infection at the injection site within a few days. Some of these infections can be serious. Call your healthcare professional right away if you have any of the following at an injection site: redness that does not go away, swelling, tenderness, or the area feels warm to the touch.

Tell your healthcare professional about all of your medical conditions, especially if you have asthma, a history of depression, thyroid problems, Parkinson’s disease, diabetes, high blood pressure or heart problems, have any other medical conditions, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Be sure to also tell your healthcare professional all the medicines you take, especially medicines for asthma. If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have longer lasting side effects when you use EPIPEN or EPIPEN JR.

Common side effects include fast, irregular or “pounding” heartbeat, sweating, nausea or vomiting, breathing problems, paleness, dizziness, weakness, shakiness, headache, feelings of over excitement, nervousness or anxiety. These side effects usually go away quickly if you lie down and rest. Tell your healthcare professional if you have any side effect that bothers you or that does not go away.

Indications (the following information applies to both Epipen and its Authorized Generic)

EPIPEN and EPIPEN JR  Auto-Injectors are for the emergency treatment of life-threatening allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for people who are at increased risk for these reactions. EPIPEN and EPIPEN JR are intended for immediate administration as emergency supportive therapy only. Seek immediate emergency medical help right away.


 Please see the full Prescribing Information and Patient Information for EPIPEN.

Please see the full Prescribing Information and Patient Information for the Authorized Generic for EPIPEN.

For additional information please contact us at 800-796-9526.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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