Anaphylaxis management

Because anaphylaxis symptoms may progress rapidly and become life-threatening, it is important that treatment with epinephrine be initiated promptly.1-3 Immediate intervention tactics involve assessing the airway, breathing, circulation and level of consciousness, as well as administering epinephrine.1,2

Is epinephrine appropriate treatment for all cases of anaphylaxis?

According to guidelines developed by the National Institutes of Health and the National Institute of Allergy and Infectious Diseases (NIH-NIAID), “epinephrine is the first-line treatment in all cases of anaphylaxis. All other drugs have a delayed onset of action.”4 Anaphylaxis is triggered by a wide range of allergens, including, but not limited to foods, insect stings and bites, medications and latex.1,3,5

When a second dose of epinephrine may be warranted

The NIAID food allergy guidelines recommend having access to two epinephrine auto-injectors. More than two sequential doses of epinephrine should only be administered under medical supervision.

It is important to communicate to your patients that if they, their child or someone they’re caring for shows signs or symptoms of an anaphylactic reaction, they should inject EpiPen® or EpiPen Jr® (epinephrine injection) Auto-Injector immediately and seek emergency medical attention.2,5,6 More than two sequential doses of epinephrine should be administered only under direct medical supervision.6