Questions to Ask Your Healthcare Professional

Key Facts about Anaphylaxis

1. Severe allergic reactions (anaphylaxis) are serious and, unless treated quickly, can result in major illness or death.
2. It is caused by exposure to allergens like food, insect stings, drugs, latex and exercise.
3. Symptoms include itchiness, swelling, breathing difficulty, dizziness and nausea.

Questions to Ask Your Healthcare Professional

• How can I tell if I am at risk of a severe allergic reaction (anaphylaxis)?
• How can I tell if I am allergic to a particular allergen or just intolerant of it?
• If I had a reaction to an allergen in the past, will it happen again?
• What are my options for treating anaphylaxis if it were to occur?
• If some members of my family have allergies, might I have them too?
• How can I help my child avoid exposure to a known allergen?
• What should I tell my child's teachers and caregivers about his/her allergies?
• What is the best way to prevent a severe allergic reaction?
• What is immunotherapy and can it be used to treat severe allergies?
• Should I wear an allergy alert ID bracelet?

Indications

EpiPen® and EpiPen Jr® Auto-Injectors (0.3 and 0.15 mg epinephrine) are for the emergency treatment of severe allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for patients who are at increased risk for these reactions.

EpiPen and EpiPen Jr Auto-Injectors are designed for you to use immediately in an emergency, to treat an allergic reaction fast and give you time to get to a hospital or medical center. EpiPen and EpiPen Jr Auto-Injectors are not a substitute for emergency medical treatment.

Important Safety Information

Each EpiPen Auto-Injector contains a single dose of a medicine called epinephrine, which you inject into your outer thigh. DO NOT INJECT INTRAVENOUSLY. DO NOT INJECT INTO YOUR BUTTOCK, as this may not be effective for a severe allergic reaction. In case of accidental injection, please seek immediate medical treatment.

Epinephrine should be used with caution if you have heart disease or are taking certain medicines that can cause heart-related (cardiac) symptoms.

Side effects may include an increase in heart rate, a stronger or irregular heartbeat, sweating, nausea and vomiting, difficulty breathing, paleness, dizziness, weakness or shakiness, headache, apprehension, nervousness, or anxiety. These side effects usually go away quickly, especially if you rest. If you have high blood pressure or an overactive thyroid, these side effects may be more severe or longer lasting. If you have heart disease, you could experience chest pain (angina). If you have diabetes, your blood sugar levels may increase after use. If you have Parkinson's disease, your symptoms may temporarily get worse.

Talk to your healthcare professional to find out if you should be prescribed an EpiPen and EpiPen Jr Auto-Injector.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For additional information please contact us at 800-395-3376